Abstract Background The persistence of latent HIV-1 reservoirs knob creek apparel is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral therapy.It is thus crucial to understand the molecular mechanisms involved in the establishment, maintenance and reactivation of HIV-1 latency.Since chromatin
Dynamic capabilities, Marketing Capability and Organizational Performance
The goal of the study is to investigate the influence of dynamic capabilities on organizational performance and the role of marketing capabilities as a mediator maglione loro piana in this relationship in the context of private HEIs in Brazil.As a research method we carried out a survey with 316 IES and data analysis was operationalized with the te
THE THEORY OF ESSENTIAL FACILITIES. THE PRINCIPLE OF ACCESS TO INVENTION IN CASE OF ABUSIVE REFUSAL TO LICENSE
Essential facilities designate specific inputs which are essential for the production of oolution light up other downstream goods.Inputs are situated upstream and so are eligible for intellectual property protection.In order to foster competition in the downstream, holders of these inputs should be forced to give access to potential users, by offer
Rationale for an Association Between PD1 Checkpoint Inhibition and Therapeutic Vaccination Against HIV
The pathogenesis of HIV immunodeficiency is mainly dependent on the cytopatic effects exerted by the virus against infected CD4+ T cells.However, CD4+ T cell loss cannot be the only pathogenic factor since severe opportunistic infections may develop in HIV infected patients with normal CD4+ T cell counts and since the recent START study indicated t